Detalhe da pesquisa
1.
Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance.
Nature
; 623(7989): 1053-1061, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37844613
2.
Machine learning estimation of human body time using metabolomic profiling.
Proc Natl Acad Sci U S A
; 120(18): e2212685120, 2023 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37094145
3.
Assessing cognitive toxicity in early phase trials - What are we missing?
Psychooncology
; 31(3): 405-415, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34651364
4.
Investigating the phosphinic acid tripeptide mimetic DG013A as a tool compound inhibitor of the M1-aminopeptidase ERAP1.
Bioorg Med Chem Lett
; 42: 128050, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33887439
5.
A systematic molecular and pharmacologic evaluation of AKT inhibitors reveals new insight into their biological activity.
Br J Cancer
; 123(4): 542-555, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32439931
6.
Effect of acute total sleep deprivation on plasma melatonin, cortisol and metabolite rhythms in females.
Eur J Neurosci
; 51(1): 366-378, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30929284
7.
Metabolomic changes of the multi (-AGC-) kinase inhibitor AT13148 in cells, mice and patients are associated with NOS regulation.
Metabolomics
; 16(4): 50, 2020 04 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32285223
8.
International Ring Trial of a High Resolution Targeted Metabolomics and Lipidomics Platform for Serum and Plasma Analysis.
Anal Chem
; 91(22): 14407-14416, 2019 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31638379
9.
Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.
Angew Chem Int Ed Engl
; 58(2): 515-519, 2019 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30431220
10.
Investigation of metabolites for estimating blood deposition time.
Int J Legal Med
; 132(1): 25-32, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-28780758
11.
Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy.
Br J Cancer
; 116(9): 1166-1176, 2017 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334731
12.
Interlaboratory Reproducibility of a Targeted Metabolomics Platform for Analysis of Human Serum and Plasma.
Anal Chem
; 89(1): 656-665, 2017 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27959516
13.
A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.
Nat Chem Biol
; 11(12): 973-980, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26502155
14.
Pyrido[3,4-d]pyrimidin-4(3H)-one metabolism mediated by aldehyde oxidase is blocked by C2-substitution.
Xenobiotica
; 47(9): 771-777, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-27618572
15.
Effect of sleep deprivation on the human metabolome.
Proc Natl Acad Sci U S A
; 111(29): 10761-6, 2014 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25002497
16.
Synthesis and Evaluation of a 2,11-Cembranoid-Inspired Library.
Chemistry
; 22(16): 5657-64, 2016 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26929153
17.
Discovery of potent and selective CDK8 inhibitors from an HSP90 pharmacophore.
Bioorg Med Chem Lett
; 26(5): 1443-51, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26852363
18.
7-(Pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine-based derivatives for kinase inhibition: Co-crystallisation studies with Aurora-A reveal distinct differences in the orientation of the pyrazole N1-substituent.
Bioorg Med Chem Lett
; 25(19): 4203-9, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26296477
19.
Dependence of Wilms tumor cells on signaling through insulin-like growth factor 1 in an orthotopic xenograft model targetable by specific receptor inhibition.
Proc Natl Acad Sci U S A
; 109(20): E1267-76, 2012 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22529373
20.
Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase.
J Med Chem
; 67(2): 1061-1078, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38198226